253 Virgin Olive Oil Benefits that provide strength and stability to the clot. Once tissue repair is complete, fibrinolysis occurs to remove the residues of the clot. - haemostasis The overall process by which haemostasis is achieved and maintained. - extrinsic pathway A coagulation initiation pathway that depends on factors not normally present in the bloodstream, such as tissue factor, which originates from cells outside the vascular system (e.g., subendothelial fibroblasts). (See also: “Platelet Function”, “Thrombosis”, and “Tissue Factor”) HAEMOSTATIC SYSTEM (See HAEMOSTASIS) HDL - HDL cholesterol (See LIPIDS / Concepts / Cholesterol / HDL-cholesterol) HDL cholesterol (See LIPIDS / Concepts / Cholesterol) HEALTHY AGEING / SATISFACTORY AGEING (See AGEING)) HEART FAILURE A serious condition in which the heart is no longer able to pump blood efficiently either to the lungs (right-sided heart failure) or to the rest of the body (left-sided heart failure). It can be caused by various cardiac conditions (valve disorders, infections, arrhythmias, etc.), or by non-cardiac factors (anaemia, thyroid dysfunction, including both hypothyroidism and hyperthyroidism, etc.). As the heart’s pumping function becomes less effective, blood may accumulate in other parts of the body (lungs, liver, gastrointestinal tract, legs, etc.), a condition known as congestive heart failure. Other common symptoms include shortness of breath, unusual fatigue, and difficulty breathing when lying flat. HEMOSTASIS (See HAEMOSTASIS) HEPATIC FIBROSIS A pathological process in the liver characterised by the accumulation of extracellular components of connective tissue, such as collagen fibres, which form scar-like structures in the liver. (See also “Fibrosis”) HOLTER MONITORING A portable system used to continuously monitor heart rhythm or blood pressure over a period of 24 hours or more, to help diagnose certain conditions. Small electrodes, consisting of metal plates that conduct electrical signals, are attached to the chest and connected by wires to a battery-powered device called a Holter monitor. This device is typically worn in a pouch around the neck or waist, or placed in a pocket.
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