107 Virgin Olive Oil Benefits Ageing is an endogenous, progressive, and universal process associated with an increase in disease frequency. It is a physiological development that can be partially controlled by diet. For instance, dietary fat can condition ageing through its ability to change the composition of biological membranes, including mitochondrial ones which are actively involved in the process. The antioxidant capacity of virgin olive oil is a key factor since oxidation has been directly associated with ageing. Many studies in animal models and, to a lesser extent in humans, have shown that continuous life-long virgin olive oil intake promotes less oxidizable mitochondrial membranes, making the body better able to cope with age. KEYWORDS: Monounsaturated fatty acids, polyunsaturated fatty acids, oxidative stress, mitochondriaa ABBREVIATIONS: ATTICA: (ATTICA study). A study focused on nutrition and health performed in the Attica province (Greece) in which Athens is the main city. MEDIS: (“MEDiterranean ISland study”). A longitudinal study focused on nutrition and health performed in Mediterranean islands with participants aged >65. The objective was to evaluate the relationship between sociodemographic, clinical, lifestyle (physical activity and nutritional habits), and psychological characteristics and cardiovascular risk factors and a successful ageing. The participants were free from chronic diseases at the beginning of the study which started in 2005 with follow-ups at 5 and 10 years. adstract
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