338 OLIVE OILS AND HEALTH enzymes responsible for metabolising endogenous molecules, due to their remarkable enzymatic versatility. This metabolic process is known as detoxification. In some cases, the original compound is inactive and only becomes active after metabolism,sometimes resulting in a beneficial effect (as with certain drugs), or in harmful outcomes if it is converted into a toxin or carcinogen. The metabolites generated over time can contribute to oxidative stress, which is normally counteracted by the body’s antioxidant defences and dietary antioxidants. However, if these protective systems are overwhelmed or depleted, oxidative stress may develop, leading to lipid, protein, and DNA damage, etc., and subsequent health problems.
RkJQdWJsaXNoZXIy Njg1MjYx