OLIVE OILS AND HEALTH 186 This molecule is produced by our cells and binds to those responsible for triggering the inflammatory response. Current CoViD-19 treatment also includes antiviral drugs such as remdesivir, which inhibits the enzyme involved in the virus genome replication, and regeneron, which blocks the binding of the virus to the cells, thus avoiding their infection. As has been previously described, fats and oils have anti-inflammatory activity and are recommended in CoViD-19 treatment, and also for preventive purposes. Olive oil, especially extra virgin olive oil (EVOO), has anti-inflammatory properties. Unlike fats rich in polyunsaturated fatty acids, such as fish oils, it does not significantly reduce the body’s defence against infections. Fish oils are known for their anti-inflammatory effects and are recommended for people infected with SARS-CoV-2. They can also be used preventively by those not infected. However, we must highlight a risk: some fats rich in polyunsaturated fatty acids can weaken the immune response so much that they increase the risk of infections. In contrast, olive oil, particularly EVOO, offers anti-inflammatory benefits without causing immunosuppression. This makes it a safer option that doesn’t increase our vulnerability to infections. 15.7. References – For further knowledge Puertollano MA, Puertollano E, Álvarez de Cienfuegos G, de Pablo MA. Olive oil and immune resistance to infectious microorganisms. In: Preedy VR, Watson RR, editors. Olives and olive oil in health and disease prevention, Oxford Academic Press, Oxford. 2010. p. 1039 – 1047. Puertollano MA, Puertollano E, Álvarez de Cienfuegos G, de Pablo MA. Aceite de oliva, sistema inmune e infección (Olive oil, immune system and infection). Nutr Hosp 2010;25:1 – 8. Calder PC. n-3 polyunsaturated fatty acids and cytokine production in health and disease. Ann Nutr Metab 1997;41:203- 234. Yaqoob P. Fatty acids as gatekeepers of immune cell regulation. Trends Immunol 2003;24:639-645.
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